FREE RADICALS

CARNOSINE

Animal Study

1. Doses of carnosine (200 mg per liter) increased the lifespan of male Drosophila melanogaster flies by protecting against free radicals.

Bull Exp Biol Med. 2002 Jun;133(6):559-61. 
Effect of carnosine on Drosophila melanogaster lifespan.
Yuneva AO, Kramarenko GG, Vetreshchak TV, Gallant S, Boldyrev AA.

N-acetyl L-cysteine (NAC)
Animal Study

2. Treatment with the free radical scavenger, N-acetyl-L-cysteine (0.2 – 2.0 mg per
milliliter in drinking water) after an injection to induce encephalomyelitis prevented the development of encephalomyelitis in mice.

J Neuroimmunol. 1994 Feb;50(1):35-42. 
Oral administration of the oxidant-scavenger N-acetyl-L-cysteine inhibits acute experimental autoimmune encephalomyelitis.
Lehmann D, Karussis D, Misrachi-Koll R, Shezen E, Ovadia H, Abramsky O.

Animal Study
(1 gram = 1000 milligrams)

3. Doses of N-acetyl-L-cysteine (1 gram per kilogram body weight/day) administered
with doses of ethanol (6 gram per kilogram body weight/day) protected rat brain
cells from ethanol injury.

Tohoku J Exp Med. 2002 Oct;198(2):71-7. 
N-acetylcysteine reduced the effect of ethanol on antioxidant system in rat plasma and brain tissue.
Aydin S, Ozaras R, Uzun H, Belce A, Uslu E, Tahan V, Altug T, Dumen E, Senturk H.

NARINGIN
Animal Study

4. Doses of naringin (2 mg per kilogram body weight) protected mouse bone marrow
from free radical, chromosomal damage caused by radiation.

Mutagenesis. 2003 Jul;18(4):337-43. 
Naringin, a citrus flavonone, protects against radiation-induced chromosome
damage in mouse bone marrow.
Jagetia GC, Venkatesha VA, Reddy TK.

Animal Study

5. Doses of superoxide dismutase (48,000 IU) protected dog lungs from free radical damage.

Eur J Pharmacol. 1998 Mar 5;344(2-3):231-9. 
Lecithinized superoxide dismutase attenuates phorbol myristate acetate-induced injury in isolated dog lung.
Miyahara T, Shibamoto T, Wang HG, Koizumi T, Honda T, Kubo K, Sekiguchi M, Koyama S.
PMID: 9600659