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A Publication of the The Arthritis Trust of America

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Publisher certifies that this is an independent news report made as accurately as possible, and further certifies that no drug company, medical doctor, or medically related institution has any financial interest in the sale and proceeds of this publication or the medicines recommended. Publisher further advises that all treatment should be through a licensed physician, and that we cannot be responsible for mal-application or mis-application or inappropriate treatment of any kind. Voluntary contributions to the tax-exempt, charitable The Roger Wyburn-Mason and Jack M. Blount Foundation for Eradication of Rheumatoid Disease, Inc., (The Rheumatoid disease Foundation/The Arthritis Trust of America, 7111 Sweetgum Drive SW, Fairview, Tn 37062-9384), will be used for the purpose of furthering research and in communicating discoveries.

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Library of Congress Cataloging Number 82-73215

ISBN 0-931150-12-4

c1982 by Anthony di Fabio

c1983, 1984, 1985 revised editions by Anthony di Fabio

revised 1994 by Stephan Cooter, Ph.D.

"Louis Pasteur, Medical Quack," John W. Campbell, Jr.

Copyright by the Cond‚ Nast Publications, Inc.

first published in Analog Science Fiction/Science Fact.

Published by The Arthritis Trust of America

7111 Sweetgum Drive SW, Suite A, Fairview, Tn 37062-9384

(615) 799-1002

Typesetting and Layout by AC Projects, Inc.

Franklin, TN 37064

Originally Printed in Washington, DC, USA

Second Printing in Franklin, TN

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Dedication and Acknowledgment

This book is dedicated to two brilliant and brave men, Professor Roger Wyburn-Mason, who one day should receive the Nobel Prize in Medicine, and Dr. Jack M. Blount, who should at least receive the Congressional Medal of Honor for bravery in the face of hostile forces; with special mention also for Dr. Robert Bingham whose open-mindedness and foresight brought Professor Roger Wyburn-Mason's work overseas, John R.A. Simoons, Ph. D., for persistence in bringing this work to attention of academia and drug manufacturers, Dr. Archimedes A. Concon, for vision in applications, and Dr. Eugene S. Wolcott who knows why; and an additional personal thanks to L. Ron Hubbard and John W. Campbell, Jr. for providing the author with vision on the coin's other side.

Physicians and Scientists Advisory Committee of The Roger Wyburn-Mason and Jack M. Blount Foundation for Eradication of Rheumatoid Disease, The Rheumatoid Disease Foundation, now The Arthritis Fund have been particularly helpful in creating new medical protocol and in dissemination rheumatoid disease information, for which a deep, heartfelt thanks - .

This book is a report of the life-time work of Professor Roger Wyburn-Mason, who had for more than twenty-six years researched the roles of pathogenic protozoa in human disease as a protozoologist, pharmacologist and rheumatologist.

In collaboration with his wife, and over twelve years, he wrote a monumental work, which may revolutionize the diagnosis and treatment of many chronic and dangerous illnesses. The work is titled The Causation of Rheumatoid Disease and Many Human Cancers - A New Concept in Medicine.1

The material that follows in this book for the most part is taken from Professor Roger Wyburn-Mason's primary book and/or his Addenda. (The Causation of Rheumatoid Disease and Many Human Cancers - A New Concept in Medicine - A Pr‚cis and Addenda, Including the Nature of Multiple Sclerosis) with his permission. The Memoriam below is from the new cover of Roger's Addenda, his last book to be published.

We also wish to acknowledge and to share with the reader our appreciation for the more than generous cooperation of the many people who helped us. They are: Branch Owen Adkerson (Franklin, TN, USA), Stan J. Bardo (Pietermaritzburg, Republic of South Africa), Frederick H. Binford (Nashville, TN, USA), Warren B. Causey (San Antonio, TX, USA), E. Harrison Clark (Alexandria, VA, USA), Terry Crommelin (Perth, Western Australia), Robert Edmonds (Hollywood, CA, USA), George Hay (London, England), Kay Hitchen (Southampton, Hampshire, England), Carl Hosch, Jr.(Atlanta, GA, USA), Bob Kemp (Beebe, AR, USA), John Kern, (Brentwood, TN, USA), Jean Lancaster (Philadelphia, MS, USA), Gus and Patty J. Prosch, Jr. (Birmingham, AL, USA), Paul K. Pybus (Pietermaritzburg, South Africa), Carl J. Reich (Calgary, Alberta, Canada), Larry L. Roberts (Nashville, TN, USA), Don and Nancy Vansant(Nashville, TN, USA), Joan Wyburn-Mason (London, England), Vaughn Young (Hollywood, CA, USA), and many others, some of whom prefer anonymity.

In Memoriam

Roger Wyburn-Mason Oct. 2, 1911 - June 16, l983

When I was at last cured of the dreaded, crippling rheumatoid arthritis, I never dreamed of embarking on a world-wide challenge to professional rheumatologists, the gigantic and ineffective Arthritis Foundation, and the American petrochemical industry that siphons $15,000,000,000 a year in the United States of America from the sick and the lonely, chiefly for aspirin substitutes that simply treat symptoms, and not causes.

Somehow the Good Lord has seen fit to successfully guide my path - along with other determined, sincere people - to bring the good message to all: there is a cure! it is simple! it is cheap! it is available everywhere!

My book Rheumatoid Diseases Cured at Last (1982) was monitored by professor Roger Wyburn-Mason, and based on his original work, The Causation of Rheumatoid Disease and Many Human Cancers (1978). My book was designed for the ailing to find hope, to convince them, to be carried to their family physician for further interpretation where they would be treated.

My small book also launched The Roger Wyburn-Mason & Jack M. Blount Foundation for Eradication of Rheumatoid Disease, The Rheumatoid Disease Foundation, now The Arthritis Fund, which is now successfully off and running, millions of messages spreading the word. Many fine humanity-conscious physicians and non-physicians are now members, and working toward common goals set by Professor Roger Wyburn-Mason.

Some six weeks ago I wrote to Roger, asking that he please include a summary of his professional life and writings. I argued that while his work ought to stand on its own two feet, professional humans, like other humans, simply were more impressed with the number of "brownie points" and "merit badges" than with whether or not the work was "scientifically valid" - not meaning, of course, to disparage either the Boy or Girl Scouts, (I was an active Boy Scout) but rather to emphasize the sad state in which the so-called professional scientific community finds itself - where "altitude" and "prestige" is of more consequence than scientific validity.

Reluctantly, Professor Roger Wyburn-Mason sent this, his last letter before the Good Lord called him on June 16, l983.

"I was born in Monmouthsire, England. On my mother's side I am a descendent of Bishop Stephen Gardiner, who was Lord Chancellor of England, that is the most powerful person in the country after the Monarch in the reign of King Henry VIII, King Edward VI, Queen Mary and first and Queen Elizabeth the first. He conducted the marriage of King Philip II of Spain to Queen Mary the first of England in Winchester Cathedral, where he is buried in a magnificent tomb. My mother's cousin was the former Prime Minister of New Zealand, Mr. Nash. My godfathers were the greatest English Composer, Dr. Ralph Vaughn Williams of Cambridge University and now buried in Westminster Abbey, and the historian H.A.L. Fisher, the head of New College Oxford both of whom held the decoration of Order of Merit (O.M.), the highest honor that can be bestowed by the Monarch.

"I attended a public school (a public school in England is the opposite of one in the United States, being privately as opposed to state owned and includes such distinguished Institutions at Eton, Harrow and Winchester Colleges). At the end of school years I took the necessary final examinations and gained the top marks in the whole of Great Britain and was awarded a State Scholarship and an Open Scholarship to Christ's College, Cambridge (founded in 1405 A.D.), where the poet John Milton and the great scientist Charles Darwin were also students. Here I occupied the same rooms as those of Darwin himself.

"At Cambridge I obtained double first class honours in the final examinations for the B.A. (Bachelor of Arts) degree. I also represented my University at Rugby football and Athletics. At the end of my period as an Undergraduate, I remained in Cambridge as a Bachelor Fellow of the College and did research in pathology and particularly protozoology. I afterwards was awarded the degree of M.A. (Master of Arts) a higher degree and the only University scholarship awarded to graduates completing their clinical studies at a London Hospital where I finally obtained my M.B. (Bachelor of Medicine) and B. Chir. (Bachelor of Chirurgerie [British archaic spelling of Surgery]). I afterwards held the posts of Registrar (the equivalent of Instructor in America) in the foremost hospitals in London, namely the Middlesex Hospital, the Brompton Hospital for Chest Diseases, the National Heart Hospital, the National Hospital for Nervous Diseases and the Royal Marsden Hospital for Cancer. While at the Middlesex Hospital, I took part in the first Clinical Trials of the first sulfonamide antibiotics. While working at the National Hospital for Nervous Diseases I wrote my thesis for the M.D. (Cambridge Degree - This is a higher degree unlike it is in the United States and other countries). I also sat for M.R.C.P. (Member of the Royal College of Physicians) examination in which I obtained the top marks of all the candidates. My M.D. thesis was entitled "The vascular tumuors and abnormalities of the spinal cord and its membranes" and received with acclaim as it was the first description of these matters. It was published as a monograph and has remained the standard work on this subject. While working at the National Hospital for Nervous Diseases, I published a number of papers in medical journals and two of these described new diseases which have since been named after me, and I am the only living doctor who has such a distinction. One of these conditions describes the presentation of cancer as a peripheral neuropathy, that is a disturbance of the nerves of the limbs before any other evidence of cancer is present. The other describes a congenital blood vessel disease of the skin of the forehead, the fundus of the eye, the optic nerve and the brain.

"I later was elected Research Fellow at the Royal Marsden Hospital for research into cancer and later Research Fellow at the Royal College of Surgeons of England, where I continued my research into the nature of cancer and first isolated from all human malignant tumors and from cases of rheumatoid arthritis an hitherto unknown, very small free-living amoebae. For this I received the Ph. D. degree.

"While Working at the Royal Marsden Hospital, I discovered that human tissues affected by herpes zoster (shingles) and by herpes simplex (cold sores) which are both due to virus infections were liable to develop cancer of the skin at a later date. This was the first description of human cancer caused by a virus, and it resulted in my invitation by the late Professor Duran-Reynals, who was working at Yale University on the viral cause of human cancer, to Yale to work with him his assistant where I continued after his death. I later transferred to the Mayo Clinic and worked with the late Dr. J.W. Kernohan, the neuropathologist.

"I became convinced that while viruses cause cancer in animals, they rarely do so in man. During these years, I published many papers and monographs (books) on my researches, and as a result of these I was awarded the degree of Doctor of Science of Cambridge University (a rare honour) and elected a Fellow of my old College.

"After twenty years work on the new organism which I had discovered, I was able to show that this was the cause of rheumatoid arthritis. Furthermore, infection with species of this organism in susceptible subjects seemed to be the cause of a large proportion of cases of human cancer, which can be prevented by taking appropriate substances which kill the organism. This work has all been described in a book entitled The Causation of Rheumatoid Disease and Many Human Cancers - A New Concept in Medicine, and it has caused worldwide interest.

"After a time, it became necessary for me to return to England where I continued my work in the laboratories and wards of the National Health Service.

"Among my publications are the following:

Books

The Vascular Tumours and Abnormalities of the Spinal cord and its Membranes. Henry Kimpton, London, 1943.

Trophic Nerves. Henry Kimpton, London, 1950.

Reticulo-endothelial System in Growth and Tumour Formation. Henry Kimpton, London, 1958.

A New Protozoan, Its Relation to Malignant and Other Diseases. Henry Kimpton, London, 1964.

The Causation of Rheumatoid Disease and Many Human Cancers - a New Concept in Medicine. Iji Publishing Co. Tokyo, Japan, 1978.

A Pr‚cis and Addendum to the above. AC Publishing Co., The Arthritis Fund, Franklin, TN 37064, 1983.

Some Papers

"On some anomalous forms of amaurotic idiocy and their bearing on the relationship of various types." Brit. Journ. Ophthalmol., April/May 1943, p. 145-187.

"Arterio-venous aneurysm of midbrain and retina, facial naevi and mental changes." Brain, 1943, 66, 163-203 . (This is known as Wyburn-Mason Syndrome I).

"On some pressure effects associated with cervical and the rudimentary and 'normal' first ribs and the factors entering into their causation." Brain, 1944, 67, 141-177.

"A new conception of angina pectoris." Brit. Med. J., 1948. i, 972.

"Bronchial carcinoma presenting as polyneuritis." (Wyburn-Mason's Syndrome II). Lancet, 1948, i, 203.

"The significance of the reference of anginal pain to the right or left side of the body." Amer. Heart J., 1950, 39, 325-335.

"The nature of tic doulourux." Brit. Med. J., 1954, iii, 119.

"Costo-clavicular compression of the subclavian vein and its significance in relation to post operative oedema in carcinoma of the breast." Brit. Med. J., 1953, iv, 1106-1109.

"Malignant change following herpes simplex." Brit. Med. J., 1957, ii, 615-161.

"Visceral lesions in herpes zoster." Brit. Med. J., 1957, i, 678-681.

These last three articles are the first reports of a viral cause of human cancer.

"Association of gastroduodenal lesions with MeniŠr's syndrome." Brit. Med. J., 1959, i, 78-83.

"Clotrimazole and rheumatoid arthritis." Lancet, 1976, i, 489.

"The free-living amoebic causation of rheumatoid and auto-immune diseases." International Medicine, 1979, i, 20-25.

"New views on the aetiology of rheumatoid arthritis." British Medicine, August 21st, p. 12-14.

"The Naeglerial causation of rheumatoid disease and many human cancers - A new concept in medicine." Medical Hypotheses, 1979, 5, 1237-1249.

"SLE and lymphoma." Lancet, January 20th , 1979.

Roger Wyburn-Mason June 10th, 1983

Professor Roger Wyburn-Mason solved the riddle of one of man's oldest curses, and in so doing, discovered a vast panorama of formerly, and so-called, incurable diseases. He strived with every ounce of his great, God-given intellect to bring to all humanity his discoveries. We prayed to be there when he walked across the stage to receive his Nobel Prize, and other prizes that were his due - but God, in his great wisdom, decided otherwise for us, and we must accept.

To the famous names of Semmelweis, Jenner, Koch, Harvey, Ross, Lister, Pasteur, Ehrlich, Sister Kenny, and Roentgen add Wyburn-Mason - a most brilliant, brave, humanity-loving man who pursued evil forces causing them to acknowledge that humanity need not always feel pain, suffering, depression, disillusionment -.

The simple antiamoebic cures developed by Professor Roger Wyburn-Mason, M.D., Jack M. Blount, M.D., and Robert Bingham, M.D. are described herein; and corroboratory case histories are also included.

***

In Memoriam

Mrs. Joan Wyburn-Mason, the beautiful lady who patiently supported and worked with Roger Wyburn-Mason through his many brilliant medical discoveries, died March 1, l985.

Her last work, in support of her former husband, is entitled Dedication, Love and Humour, a brief biography of their life together, as told through Joan's loving eyes.

This well-written booklet is published by The Rheumatoid Disease Foundation, now The Arthritis Trust of America.

***

1. Professor Roger Wyburn-Mason's book The Causation of Rheumatoid Disease and Many Human Cancers, was originally only available in Japan at $125 each. Limited numbers have been placed in various hospital and university medical libraries, at Dr. Jack M. Blount's expense. A summary of the 479-page book, with a Pr‚cis and Addendum has been republished by The Rheumatoid Disease Foundation, now The Arthritis Society of America, for $10.

Table of Contents

Dedication and Acknowledgment................................................

Table of Contents........................................................................

Preface.........................................................................................

Chapter I: You and Your So-Called Hopeless Disease............

For the Rest of Your Life?........................................................

The Ordinary Made Hard.........................................................

Stiffness, Pain, Heat and Cold.................................................

Hopelessness.............................................................................

Traditional Treatments.............................................................

Non-traditional Treatments......................................................

So Where From Here?..............................................................

Chapter II: Dr. Jack M. Blount's "Miracle".............................

Dr. Jack M. Blount's Gift to Mankind.......................................

Dr. Blount's Story: Rheumatoid Disease is of the Entire Body..

Despair......................................................................................

Why Was I Saved?.....................................................................

"The Miracle of Professor Roger Wyburn-Mason.....................

I Experiment on Myself..............................................................

More Successful Patients............................................................

Well Again!..................................................................................

Prayer For the Entire World.......................................................

Chapter III: The Author is Also Cured.........................................

The Beginning of Arthritis...........................................................

Fatigue and Depression...............................................................

Pains Increase.....................................................................

The Discovery......................................................................

The Cure................................................................................

Chapter IV: The Miracle" Treatment......................................

Recommended Treatments................................................

The Rheumatoid Disease Foundation Protocol - Rheumatoid...

Herxheimer reaction signs and symptoms....................................

Chapter V: Cooperating Physicians and Scientists................

How to Contact Them...................................................

Table of Medicines...............................................................

A Simple Plea to Sincere Physicians - Gus Prosch, Jr. M.D.......

Chapter VI: Professor Wyburn-Mason's Theory of Protozoal

Cause of Many Hitherto Unrelated Diseases...................

The Prevailing Medical Theory..............................................

Wyburn-Mason's Findings.............................................

State of Art in Medicine........................................................

Primary Source of Rheumatic Diseases................

Roger Wyburn-Mason Letter June 1983..................................

Chapter VII: Amazing Implications of the Protozoon Discovery.

Broad-spectrum Antibiotics.........................................

Broad-spectrum Antiamoebics...................................................

Isolation of the Amoeba.........................................................

Collagen Diseases...............................................................

Susceptibility..............................................................................

Present Rheumatology Practices Unscientific.......................

Important Note....................................................................

Chapter VIII: Case Histories...................................................

Based on Wyburn-Mason's Work -......................................

Introduction.......................................................................

Successive cases treated with furazolidone.......................

Successive cases treated with allopurinol..........................

Conclusion..........................................................................

Based on Madden's and Mendel's work --...........................

Introduction .......................................................................

Successive cases treated with tinidazole ............................

Conclusion...........................................................................

Based on Concon's Work --..................................................

Introduction..........................................................................

Successive cases treated with metronidazole.......................

Conclusion.............................................................................

Based on Bingham's Report --.................................................

Introduction.............................................................................

Effects of treatment with clotrimazole....................................

The Treatment of Rheumatoid Disease With

Anti-protozoal Drugs -A preliminary Report............................

Comparative Results of Treatment With Other Drugs.............

Conclusion................................................................................

Irony..........................................................................................

Roger Wyburn-Mason Letter May 1983.....................................

Chapter IX: Correspondence, Testimonials, and Book Report...

From Dr. Paul K. Pybus............................................................

From Bob Kemp.........................................................................

From A.W. Hamilton...................................................................

From E.H.C.................................................................................

Interviews....................................................................

Letters to and on File with Dr. Jack M. Blount............................

Book Report by Dr. Robert Bingham......................................

Adequate Treatment by Dr. Robert Bingham................................

Letter by Dr. Jack M. Blount..............................................

More Letters........................................................................

Chapter X: Is it Ethical to Deny the Sick?.............................

Children Sick Forever -- ..................................................

The Right to Try!........................................................

Vested Interests.............................................................

Definition of a Quack............................................................

I Pray That You Will Be Healed, Too!.....................................

Chapter XI: Treatment of Osteoarthrosis, Osteoporosis Rheumatoid

Arthritis Pains and Element of Proper Nutrition........................

The "Aging" Disease..............................................................

The Rheumatoid Disease Foundation Protocol -- Osteoarthritis........

Injection Points for Intraneural Injections................................

Chapter XII: The Past and the Future........................................

The BCF Syndrome..................................................................

The Rheumatoid Disease Foundation [The Arthritis Trust of America]......

Donations....................................................................

Chapter XIII: Dr. Jack M. Blount's Suspended Sentence......

The Board Hearing....................................................

References....................................................................

Physician & Scientist Advisory List.........................................

Donation and /or Order Blanks........................................................... last page

The Roger Wyburn-Mason and Jack M. Blount Foundation ........ Back Cover

Photographs and Drawings

Professor Roger Wyburn-Mason and Dr. Jack M. Blount............

Left hip of Jack M. Blount, M.D., December 11, 1975.................

Right hip of Jack M. Blount, M.D., December 11, l975..................

Right Hip of Jack M. Blount, M.D., after prosthetic implant, March 21, 1976..............................................................

Photograph of a Limax amoeba............................

ozoite............................

Cysts of Limax amoebae after migration........................................

Drawing of apparatus used to separate Limax amoebae...............

Schematic Drawing I: Probable Cause of Sciatica Pain in Osteoarthrosis......

Schematic Drawing II: Nerve Sites for Intraneural Injection.......

Schematic Drawing III: Nerve Sites for Intraneural Injection.....

Schematic Drawing IV: Nerve Sites for Intraneural Injection...........

Preface

Cooperating physicians have successfully treated tens of thousands of patients afflicted with so-called incurable rheumatoid diseases using a low-cost, simple medical procedure.

The American Medical Association estimates some 13 million Americans seek relief from rheumatoid arthritis. Three million are restricted in their daily activities. Seven hundred thousand cannot do useful work, keep house, attend school or enjoy recreational activities.

The April 24, 1983 Arthritis Foundation National Telethon (out of Nashville, TN) stated that one out of every three people will suffer from some form of arthritis, that one person contracts the disease every 33 seconds.

Dr. Carolyne K. Davis1 of the U.S. Department of Health and Human Services stated that the U.S. Medicare program costs the U.S. Government about one billion dollars annually for rheumatoid diseases; and that probably an equal annual amount is spent through State Medicaid programs, totaling U.S. Citizens about two billion dollars per year for treatment and care of those afflicted with the dreaded disease.

At least one-half billion per year in lost wages is reported by The Meridian Star.2

Others3 estimate that 31 million Americans of all ages suffer from arthritis, that it attacks a million new patients a year, and costs the national economy about $15 billion annually.4

For each male who suffers, there are three females. The symptoms often appear between ages of 20 and 35 with weakness, fever, loss of appetite and weight loss. One or more of the smaller joints becomes inflamed and swollen. Acute, painful inflammation migrates from one joint to another. Mental depression is common.

Attacks may develop gradually, or suddenly with dramatic seizure. Pain and inflammation may come and go for no apparent reason. The disease may affect children and produce stunting of growth and gross deformities.

Considering the insidious nature of rheumatoid diseases, its many forms of symptoms and its long-term degenerative activity on your body, sometimes extending from birth onward, apparently this book is for you, your relatives and your friends!

***

1. Davis, K. Carolyn, Letter to Senator James Sasser, September 1, l982, transmitted by letter to author by Senator James Sasser September 23, l982.

2. The Meridian Star, "The Arthritis Foundation - Distributing Information to Those with the Affliction," Meridian, MS, February 24, l983.

3. The Scanner, Volume 1, Number 4, Fall 1981, The Arthritis Institute of the National Hospital for Orthopaedics and Rehabilitation, 2455 Army Navy Drive, Arlington, VA 22206, p. 1.

4. E. Harrison Clark reports that Barron's and Wall Street Journal report a figure of $1.5 billion, or a little less for pain-killers.

Chapter I

You and Your So-called Hopeless Disease

For the Rest of Your Life?

So, you've been told you have rheumatic arthritis, and there is no cure! For the rest of your life, you must watch your fingers and toes and arms and legs twist and turn and torture themselves into grotesque shapes that offend each eye and spirit!

When you awake each morning, your fingers and other joints are swollen, red and they burn as if held to a slow-roasting fire. You flex them and sharp pains make you grimace. Stiffened and puffy, your fingers feel like not you, like some burning, sausage-like appendages that were fastened on by instant glue during the night.

Gingerly protecting each joint, you slide carefully from your over-soft mattress. Oh, how it hurts to reach for clothing! Easy now! Not too fast, not too hard! Ouch! How that hurts! You wince, but go on dressing, though slowly. What else can you do?

The Ordinary Made Hard

Someone has tightened the coffee jar lid too much. A flash of resentment stirs as you wonder why others cannot understand, and why they cannot help you more by anticipating your weakness. Again pain forces your immediate attention. It's everywhere, at each joint -- the terrible, long-lasting, daily increasing pain....

Dare you risk injury to finger joints by fighting the coffee jar top this morning.

But you need the stimulation, the black, warm brew, something --anything -- to lighten depression, to sway your outlook...

So you struggle with the cap, gripping down on it, squeezing it and grimacing again, while sharp pains make you want to scream aloud -- and then -- at last -- the jar cap moves ever so slightly. Relaxing your fingers permits pain to diminish somewhat, and then you staunchly tackle the lid again.

You pour the steaming coffee ever so carefully and you hold it ever more gingerly. You must not place your fingers about the warm cup, for every finger joint will burn with a fury as though a small, hot laser beam were focused in them. And so it is with cold items as well. Are you one of those who wisely insulates all cups and glasses?

Such are the once easy chores that now loom larger than life itself!

Perhaps you use special tools designed just for invalids with incurable arthritis: A wide-band holder for jar caps that multiplies weakened muscles and applies increased friction about the cap; a bathtub grip-bar (what a terrifying experience, that old-fashioned bathtub); an elevated toilet set; buttoning devices for shirts, coats, blouses; a special device for turning on and off faucets at kitchen or shower (what an absurdly simple act that was once); long handles designed to reach clothing on the floor, and to permit ease in hanging them; special hooks and handles for special eye and needle affairs for tying shoe-laces - the mechanical devices are endless as the disease works into every muscle-fiber and joint.

Stiffness, Pain, Heat and Cold

How people comment about your hyperactivity! What they don't understand is that you sit or stand or lay in one position overlong, you become stiff and your joints ache excruciatingly. So you move -- here, there, everywhere -- all the time!

Do your hands and feet feel cold? Do you sweat night after night, with a terrible burning?

Your walking gait is changing; your skin bruises more easily and it has an increased fragility. Nodules have appeared in skin tissue, especially over points of pressure or friction. If you're bedridden the nodules will be found at the posterior portions of head, trunk and spine.

You might have developed skin ulcers or difficulties of another kind inside your lungs, or any of a dozen other physical problems that at first glance do not appear to be related to arthritis.

But you're probably one of the lucky ones, one of those who can still function, still determine your own physical course daily, still decide for yourself. What of those whose disease has progressed beyond, and now must lie bedridden, or rely on a wheelchair, and must be lifted and towed everywhere, must be dependent upon others, not daily, but hourly, for every little need, every little change, every little pleasure -- if any?

Are you still free and financially able to go to a warm climate where blessed relief may temporarily be yours ? Oh, how cold rains and winds shrivel us and compress pain upon pain!

Hopelessness

Must you lie and stare, and hopelessly dream of the blessings of suicide, the relief of drugs, the wonderful numbness of alcohol.... remembering that first visit to your doctor?

"You've rheumatic arthritis and there is no cure. Oh, we know that within the first year you may have a spontaneous remission, that perhaps as much as ten to twenty percent of our patients get better. Although sometimes even those have it come and go again.

"Remember, it isn't true that nothing can be done for this disease. Aspirin will kill the pain, and when your system can no longer tolerate aspirin, we've indomethacin, phenylbutazone and many other drugs all designed very nicely to ease inflammation and your pain; we've antimalarial drugs like chloraquine and hydroxychloraquine, and sometimes we use gold compounds, [gold compounds are now believed to interfere with and diminish the effectiveness of The Arthritis Fund treatment protocols] although I wouldn't advise it personally; and there are several others, like propionic acid derivatives and tolmectin....

"Then later, if you do not get better, we may give you cortisone shots -- adrenocorticosteroids. I'd not advise that either unless very urgent, as there are dangerous side-effects....

"Don't fret because the majority of patients with rheumatic arthritis can continue to lead active lives with varying degrees of restrictions. We must not seek a short-term solution, but plan for long-range management of your problem.

"There are no specific dietary recommendations,1 but you should maintain a good balanced diet, and there are no indications of vitamin supplementation, unless, of course, you just happen to have a special vitamin problem, which I don't believe is true for you. [Nutritional support, vitamin-mineral supplementation is now known to be vital to altering the course of arthritic problems and returning the patient to health. Specific recommendations are available from The Arthritis Fund. S.C. editor] Weight reduction -- and keeping it off -- should have a high priority.

"You must have rest, and we must determine a program of maintenance of joint function by physical measures, and also we don't want your muscles to atrophy. In other words, some kinds of exercises are a must, so long as you don't over-stress your joints.

"Then there is the inevitable depression and fatigue..."

"Depression?" you ask. "Fatigue?"

Do you need a lecture on depression and fatigue?

Sharp and dull pains bombard your each waking moment, until there is nothing left but for your analytical mind to attenuate, to close down, to push you into a state of emotional apathy that is beyond words.

Nothing, absolutely nothing on earth or beyond earth, can have meaning when you are at lowest ebb. Loved ones speak, and you groan, or turn-over, or at the very best you growl out, "I just don't give a damn!" and you mean it with every cell, every fiber of your being. Your spouse could move out at that instance, and you'd care not! Your beautiful children could be crying of ache and loneliness, and you'd care not! You could be told of inheriting a million dollars, and you'd care not! A flying saucer could land beside your bedroom window emitting five little green men, each carrying strange weapons that will evaporate anything they touch, and you' care not!

You could die at that instant, and you'd care not!

Please physician, tell us about apathy and fatigue...

Traditional Treatments

But the body recovers with rest, although with lessened vigor at each interval, and morning comes again. You struggle to dress, to remove the coffee jar lid, to move about, and to bathe and go through the motions or easing your daily load.

Time passes. Another trip to the doctor, and another. Your medicine closet bulges: besides aspirin there is now Indocinr, Butazolidinr, Motrinr, Clinorilr, Tolectinr, Naprosynr, Feldener. Each day you take one or another with increased frequency.

You may be one of those whose system rebels further, and you may suffer eternal diarrhea, or you may have developed stomach ulcers, or some other insidious problem - just when you thought your body withstood all the problems it could bear...!

Little by little, over weeks and months, you watch fingers and toes turn and bend, despite rigorous exercises, and you constantly fight pain. There is absolutely nothing that can be done, except now and then expensive physical therapy might slow the terrible deformation if conducted under proper professional conditions, -- but eventually nothing helps when the very joints and cartilage and tendons themselves have been eaten alive.

Now you've become a ranking candidate for prosthesis, those wonderful steel and plastic devices that are transplanted into joints.

Terrible you say?

Not so! Not if your life consists of unmoving, continuous staring at a colorless, lifeless ceiling above your bed, and a terrible moment by moment waiting for someone to come and move you from hither to thither.

Joint by joint is destroyed by the raging inferno of your own immunological system, your life eating up yourself, and joint by joint can, perhaps, be replaced, until there is little you left at all, or until you finally, blessedly, succumb to the greatest depression of all -- death!

You are probably intelligent enough to know your future -- you've seen so many others with this terrifying sickness. You've got choices. You can fight, do all the things your family doctor tells you to do: keep down inflammation and pain; exercise, but also rest frequently.

Non-traditional Treatments

Or, like so many of us, you can ignore medical science and technical knowledge and react to hearsay, superstition, panaceas. You know! Copper bracelets;2 cactus juice;3 special diets; [these treatments have been clinically tested by The Arthritis Fund now, and have been shown to be helpful] faith healers; mumbo-jumbo of one kind or another.

Who can blame us?

There is no hope, because there is no known cause, we've been told; and every day the depression and pain and fatigue and weakness increases, as does the bending and twisting and distortion of ourselves.

You look in the faces of loved ones, spouses and children and grandchildren, who move with gay abandon and carry on life with zest that was once yours -- and you wonder - can you impose this frightful crippling burden on their wonderful future? Do you have the right? Do they have the obligation to suffer with you?

What kind of terrible sin have you committed, you secretly wonder, that the Lord put this on...

Somewhere secretly deep inside you've committed yourself to ending it all at just the right time if you can find a way to do so without hurting them.

Meanwhile, any hope, something is better than nothing at all, even if that something is simply fantasized hope! Who would take that away also?

So there is nothing you can do!

Live with it, and search for relief anywhere, everywhere, and hope or give up life completely -- that's our choice!

So we search in national newspapers for special arthritis cures -- if you don't like this week's , there's always another coming along next week just to keep our fantasies alive; we look into fancy diet books and magazines and organic health journals; we carefully listen to positive sounding, authoritarian faith healers, those men who are so sure that if we will just believe a higher power will reach out with a mystical touch and lo! we are healed; oh, how we donate to their favorite causes; and we drink this briny juice, or eat that tasteless herb, or we go on special diets that would normally make us very happy if we were herbivores; or we spend time and much money getting ourselves analyzed and explained away by one school of head-shrinks or another....

No matter, all the time the terrible fires rage, our joints puff and shriek with pain, and the inexorable horrible twisting and turning marches onward!

So Where From Here?

So here you are now, with this publication, with just another claim to cure. You're pessimistic, aren't you? You have a right to be. So, keep your pessimism.

If what follows makes sense, you'll try it, like you've tried so many other things that didn't work, even when they didn't make sense. If it is science, if it is proper medical practice, it'll work. If it works, you'll be well. If it doesn't work, you're no worse off, especially since the time and cost involved in this alleged "real cure" is relatively tiny, and especially since your own family doctor can be party to the cure.

What have you to lose? A six weeks trial at very little cost under your own family physician?

That's not much compared to an endless lifetime draining cacti of their sap, or eating alfalfa, or doing some other silly thing, is it? [Distrust of these traditional medicine approaches has now turned into appreciation of these approaches for many good reasons]

Read on, if you dare, if you can stand one more hope.

And God be good to you as he has already been good to so many others....

***

1. Advice from some physicians differ. Dr. Robert Bingham, for example, states that 60% of rheumatoid arthritis patients have dietary deficiencies, and 80% have vitamin and mineral deficiencies. [This is now the consensus of most doctors associated with The Arthritis Fund.]

2. According to Professor Roger Wyburn-Mason, copper ions from a copper bracelet, on invading the bloodstream, can in fact weaken an amoebic infection which is the primary source cause of rheumatoid arthritis; but that the copper ion concentration from a bracelet source is not usually sufficient to reduce the infective population in the drastic numbers necessary. [Later, Professor Wyburn-Mason was able to demonstrate with others that pure metallic copper ions in stronger concentrations did constitute an effective treatment for many people. See The Journal of the Academy of Rheumatoid Diseases, Vol 1, No 3. S.C.]

3. According to Dr. Robert Bingham, Yucca juice is helpful for some rheumatoid arthritis patients. Its usefulness seems to come from its two most important chemical components: saponin, which facilitates the combination of oil and water aiding digestion and elimination, the other a vegetable steroid related to the cortisone family of drugs, thereby relieving symptoms. [Yucca has also been shown to have broad-spectrum antimicrobial effects in water treatment and has reversed arthritis in horses. S.C.]

[Picture]

Chapter II

Dr. Jack M. Blount's "Miracle"

Dr. Jack M. Blount's Gift to Humankind

Dr. Jack M. Blount's story is an emotionally gripping account of a man who has been to the very depths of hell and has come back to tell us how he escaped the fires. He tells his story simply, without any attempt to embellish, and it is told with a genuineness that makes you believe in his continued concern for your health and welfare. In this chapter Dr. Blount will tell his own story in his own words. Keep in mind that he is cured of the ravages of rheumatoid arthritis, that he has since treated better than 16,000 patients successfully, and that he freely gives of his knowledge to any who ask. He is a man who was active physically in his youth although his symptoms began as a systemic illness in his teens with muscle pain, metatarsalgia (pain in the foot), lumbago (pain in the back), intercostal (between ribs) pains, iridocyclitis (inflammation of eye), psoriasis (skin lesions) and that eventually he got pains in the joints, generalized arthritis with effusions (fluids into joints), carpal tunnel syndrome (compression of nerve in wrist), paresthesia (loss of feeling or perverted sensation), ulcerative colitis (sore or inflammation of colon), aseptic necrosis (death) of a femoral head for which a prosthesis (steel and plastic joint) was inserted, etc. He was reduced to total invalidism and took to alcohol, morphine-containing drugs, barbiturates and was a terminal case. He had to give up his medical practice in March 1974 and had taken steroids for more than twenty years.

Dr. Blount's Story: Rheumatoid Disease is of the Entire Body

I cured myself and more than 16,000 others of an incurable illness. RHEUMATOID DISEASE. I call it a MIRACLE.

I had rheumatoid disease. Rheumatoid disease is a disease of the entire body, not of just the joints although most of the pain and destruction seems to be in and around the joints. I was hopelessly ill.

In the Spring of 1974, I had developed aseptic necrosis (complete destruction) of my right hip socket and femoral head. I had to quit work (private medical practice) and take to the bed. The only thing that would help was a hip replacement with a prosthesis. The orthopedic surgeon that I went to said at first he would do the operation but then changed his mind giving the excuse that because I was only fifty-two years old at the time I was ineligible. They didn't know, yet, how much dependence to put on the procedure.

Despair

Despair set in; I could only lie in bed and stare at the ceiling. The cure of my illness was hopeless. No one know the cause. No one know anything useful to do for it. The usual advice was to take a lot of aspirin and learn to live with it. Pharmaceutical companies tried to improve on aspirin and gave us Butazolidinr, Indocinr, Motirnr, Tolectinr, Nalfonr, Naprosynr, Clinorilr, Meclomenr, etc. They called these "nonsteroidal anti-inflammatory" agents: all were useless except for some analgesic effect.

"Cortisone" was introduced in 1949 and was hailed for a while as the long awaited answer. It was, and still is, the quickest relief of arthritis symptoms, but it causes devastation worse than the disease. These adverse effects included hyperadrenalism (Cushing's Disease) diabetes, ulcers, weakened bone, (decalcification) etc. I took a form of this for about twenty years.

While lying in bed, my arthritis became complicated by colitis, with diarrhea of sometimes up to twenty times a day, kidney stones, alcohol, and drugs. I was in and out of hospitals repeatedly. I thought I would surely die. Friends kept sending word that they were praying for me. I often thought of committing suicide. The pain and agony were unbearable. One morning after I had accumulated about forty Seconalr capsules (sleeping pills) I swallowed them all. Four have been known to kill. I didn't want to kill myself, but I couldn't endure such perpetual agony. After some hours, my wife found me unconscious; and on finding the empty bottle, she knew what I had done. I awoke very groggy and tied to a hospital bed. After regaining enough sense to know anything at all, I wanted to know if I had been apneic. (Had I been deprived of oxygen long enough to cause permanent brain damage?) I was assured the answer was "no." Despite such an overwhelming dose of sleeping pills, I had continued to breathe adequately without supplemental oxygen or assisted breathing. This was a miracle in itself. "Somebody up There" was not ready for me.

Why Was I Saved?

Back home I kept breathing but hardly living. Why was I still here at all? I had been waiting for some earthly savior and none came. Was there some "learned University professor or researcher" somewhere who knew something to do?

The Miracle of Professor Roger Wyburn-Mason

One day in the spring of 1976, I came across an article in Modern Medicine1 entitled "Rheumatoid Disease: Has One Man Found the Cause and Cure of Rheumatoid Disease? Arthritis?," written by Robert Bingham, M.D., practicing in Riverside County, California. Dr. Bingham, orthopedic surgeon, had heard of work done by Professor Roger Wyburn-Mason, Richard Hill, Surrey, England, and had gone to England to interview the Professor. His article told about how the English researcher, practitioner, microbiologist, had determined that the etiological agent (cause) of rheumatoid disease is actually a germ, a protozoan, an amoeba, similar to the "lettuce bug" amoeba that causes dysentery. He also reported that a chemical (in fact, several chemicals) had been found that would kill the "bug" in patients without killing the patient.

He was curing people who had the disease that was killing me. The chemical (medicine) that the Professor was using successfully was called clotrimazole.

That's wonderful, but how could I get some for myself? It was not and still is not on the market anywhere in the world for systemic use.

Finally, in the Spring of 1976, my orthopedic surgeon decided to operate. They removed the upper part of the right femur with the femoral head and reamed out the acetabulum (socket). The socket was filled in with plastic to make a new one and the bone was replaced with a "comma-shaped" steel rod with the pointed end inserted down into the marrow, distally, of the remaining femur.

Now, I thought I would recover. But recovery was terrible. I still needed my pain medicine and booze. My brother became disgusted with me and had me sent to an alcoholic ward and "detox" center at the State Hospital. After a month there, I was off everything addicting except my daily early morning "Cortisone." I still had my rheumatoid disease -- my germs, the amoeba. I still had to rid my body of them. The operation seemed to give them new life.

Somehow, I remembered that clotrimazole is the active ingredient in a preparation used to treat yeast and fungus infections of the skin but it was just one part clotrimazole plus ninety-nine parts propylene glycol, car antifreeze - Prestoner. This is poisonous to man if taken internally.

I decided to telephone Delbay, the company that puts the mixture together, and see if I could get clotrimazole that hadn't been mixed. The answer was "no." They were afraid of the U.S. Food and Drug Administration.

Failing with that endeavor, I started wondering if there might be something else almost the same that would work. I looked at the word clotrimazole and focused on the azole. I looked that up in the medical dictionary and found that the parent of this is Imidazole. Somehow I remembered that I had heard that word somewhere before. I kept repeating it. Then I remembered that this is the chemical name of the medicine metronidazole, or Flagylr. I compared the formulas of the two and they looked close enough alike that I thought it was worth a trial. We had had Flagylr since 1962 and used it to cure amebiasis (intestinal) and vaginal Tricomonas infections. It was known to be able to kill both of these protozoa. I decided to try it. Later I pulled out a drawer in my bath room, and there was a bottle of one hundred Flagylr tablets. A MIRACLE! God had put the answer to my illness that close to me.

How should I take it? I realized that the small dosages that were recommended for Tricomonas and intestinal amebiasis would not do any good. If it would have, someone would have discovered it accidentally. I checked the medical text books and saw that it had been given in doses as high as three tablets, 250 mg, three times daily. That is the amount I started to take.

I Experiment On Myself

I didn't know how long to continue taking it. I didn't know if it would kill me. I realized I didn't have much to lose; therefore, I took all I had which lasted eleven days. On the morning of he eleventh day, I got nauseated while brushing my teeth -- and emptied my stomach. Then I knew I couldn't take anymore even if I had had more readily available, so I stopped.

But during these eleven days, a miracle had begun to happen. My arthritis started getting better. I awoke in the middle of he night and realized that the soreness, stiffness, and swelling had started subsiding. I looked at my hands which had been so bad and now were so much better. I couldn't hold back the tears. I started praying and thanking God.

After that, I didn't know how much was enough. I knew that I was still sick. I still had sweats and felt cold. I was bound to still have the infection. After two weeks, I decided that I needed more. I restarted taking three 250 mg tablets three times a day. I took it for eleven days more; and on the eleventh day, I got nauseated again. But I was surely improving by the day. I decided to continue this pattern.

More Successful Patients

I decided to find out if some of my former arthritis patients were brave enough to try it.

I telephoned them and invited several of them to my home, one at a time. To each I explained what it was all about. Every single one was eager to try it; nothing else had ever helped. Why not? During the Summer of 1977, about thirty of them were treated and most of them had the same good experience that I had. Some got nauseated from the start and decided to quit.

Among the thirty, was a Reverend Ethel Beall. Brother Beall not only had arthritis, but had lost a leg due to an automobile accident. The bone in the stump of the leg had gotten infected and drained constantly and was always painful. During this treatment period with Flagylr, his arthritis got better and his leg got well and stopped hurting. (Several months later he died suddenly of embolus [blood clot] while recovering from a prostate operation).

Well Again!

After 8 months, I was able to return to my private medical practice on a limited basis. I had been out three and one-half years. On September 1st 1977, I was back in the office seeing patients by appointments.

I decided to write Professor Roger Wyburn-Mason in England and tell him of my experiences. I owed him my life. He answered immediately and said that he had decided to include my case in a book he was writing. The Causation of Rheumatoid Disease and Many Human Cancers -- A new Concept in Medicine. My story appears on page 205 in the book, which was published in Japan in March 1978 by a Professor T. Koba, who obtained the original manuscript from Professor Wyburn-Mason.

We continued to correspond, and I visited with him during the Summer of 1978. He told me that he tried metronidazole at one time and it didn't work. His dosage was not adequate; he had tried giving only 250 mg three times daily. However, later he gave 750 mg three times daily, and it did work about equally as well as clotrimazole. He found other nitroimidazoles that would do the job, also.

Lately he has found three commonly used medications that are amoebicidal when used in high doses: furazolidone, allopurinol and rifampicin.

His experiments proved that Flagylr and the other nitroimidazoles are excreted slowly from the body and it is not necessary to give them on a daily basis. After giving a loading dose for two days there is an effective blood level (for killing the amoebae) for several days more. During the past six years, I have treated more than 16,000 arthritic people with very gratifying results. Some are cured of the disease while in others it has been arrested. People are now coming from all over to share in the miracle.

Professor Roger Wyburn-Mason should be nominated for the Nobel Prize in medicine.

Prayer for the Entire World

I pray that the entire world will soon know and people every where can receive the same relief that I have. What a joy I know now!

I thank God!

This information is free to whomever will take and use it. I need no wealth and seek no fame.

***

1. Modern Medicine, "Rheumatoid Disease: Has One Investigator Found Its Cause and Its Cure?" Robert Bingham, M.D., Feb. 15, 1976, pp. 38-47.

2. Published by Iji Publishing Col, Ltd., Japan ($125). Out of print. Limited number have been donated to medical libraries (USA) by Jack M. Blount, Jr., M.D. Addenda (pr‚cis and summary) available from The Arthritis Fund ($10); also write for information on loan copies of basic work.

***

Important Note

William Renforth, M.D. (Connersville, IN, USA) deserves respectful praise for research of nitroimidazoles prior to 1977, distributing information and pioneering in the use of metronidazole for treatment of Rheumatoid Disease. Dr. Archimedes Concon (Memphis, TN) following a non-amoebic theory, also effectively used metronidazole for RD prior to 1976. [From time to time historically important papers will be published by The Rheumatoid Disease Foundation, now The Arthritis Fund.]

***

Chapter III

The Author is Also Cured

The Beginning of Arthritis

In 1978, the author, at age 53, began suffering from the first pangs of rheumatoid arthritis, although at the time it was passed off as simply unimportant, transitory pains in toes and fingers and groin of unknown origin.

By choice, the author slept on a hard, cotton-pad, but slowly shoulder pains became so great that foam padding had to be overlaid.

Later visits to medical specialists brought out that the pains were from "degenerative arthritis." This diagnosis was confirmed by medical doctors at the Veteran's Administration Hospital.

Fatigue and Depression

During the following year, the author began experiencing a kind of fatigue that sapped strength and made for a hopeless despair at times which was never part of his former life. Considering the fact that the author had normally worked more than one job or position, had stayed busy seven days a week writing or teaching, or working about the yard and house, and now he had listless and suffering periodic bouts of almost complete apathy, it became clear early that something more serious was wrong. During one of these severe periods, when apathy was deepest, a misunderstanding with spouse triggered off a divorce after thirty years of marriage and ten children.

Since there seemed to be a medically defined distinction between rheumatoid arthritis and degenerative arthritis, and the writer was told (wrongly) that the former required considerable more rest and the second required active exercise of a moderate nature, this writer undertook to begin learning to play the piano and to also dance.

There's little question that the various physical exercises kept joints fluid,1 although painfully so at times, but the greatest puzzle was in the fact that within two years of the initial diagnosis of "degenerative" arthritis, the small finger on the right hand began to turn sidewise, and a typical rheumatoid arthritis and hard nodule had begun to form at this joint.

Pains Increase

Pains continued to increase at various joints; and finally, about three years into the disease, the hands began to flush red and hot and to swell, especially on arising early mornings. A great number of like symptoms lasted throughout the day.

It became almost impossible to type on the author's regular manual typewriter, because of pain kick-back to the joints.

Now the little finger on the left hand began to twist also, and all the joints at the hands began to almost glow a fiery red.

The author was having difficulty opening ordinary bottles; catsup, pickle jars, soft drinks; and the problem of opening sacks of peanuts became a procedure of first cutting the celluloid wrappings with a knife, instead of gripping and tearing with fingers.

Lifting pots and pans became an exceedingly painful chore.

Changing a tire without help was excruciatingly difficult.

His children could not understand why the author's habits had changed so drastically. Once there was nothing he would ask them to do in the way of farm or house maintenance that he, himself, would not chip in to do.

Hopelessness extended from self to family to friends, and finally even to passing acquaintances who could instinctively sense the unhappiness carried about by this rapidly aging man.

How could one make fast friends when daily his body was changing, and daily one became weaker and more ineffective with everything touched?

How could long-range commitments be kept, or strong personal relations be acknowledged? How fair is it to impose on those you love such burdens: future helplessness and twisted grotesqueness?

The author was sufficiently imaginative to know where it would end, and frankly did not want to burden anyone with what was coming. He would rather be dead than crippled and helpless and apathetic and sapping the youth and vitality of his children.

Still, the author, having had an extensive scientific background (mathematics, chemistry, physics, psychology) and also a very wide-ranging background in many different disciplines, started searching through technical literature (just as did Dr. Blount) and talking to people. Only by fortuitous accident did he come to be helped by Dr. Jack M. Blount, and it came about through this series of connections:

The Discovery

A daughter-in-law knew of the author's terrible pains and his search in the literature. She mentioned the author's search to parents. They had a friend who'd been to Dr. Blount and had been cured. They suggested to her that her father-in-law write to Dr. Blount.

Like so many others in like predicament, the author sent out the letter, not with great anticipation -- frankly, he thought he'd be fluffed off to his family doctor -- but because by now (as those with the condition know) one cannot afford to overlook anything.

Lo! A most amazing answer came back, consisting of three pages, that described Dr. Blount's own search and cure, as told in Chapter II above; and in that correspondence was embedded the name and amount of the drug necessary to produce the cure -- at no expense to the author.

The Cure

The author tried Dr. Blount's treatment, which lasted six weeks. Here's what happened:

ú After two weeks, the puffiness and redness of fingers disappeared for the first time in a half year.

ú After four weeks, the pain, depression and fatigue ended.

ú After seven weeks, the redness of finger joints nearly disappeared.

ú After seven weeks the author's attitude toward life and people changed remarkably, and again he feels like life is worth the effort, and so are people and personal relations.

There are still problems. The twisted little fingers are still distorted, and they still hurt when used. Damaged joints may never heal, but where capillaries exist, over time, healing may again proceed faster than self-destruction. There is some redness of the other finger joints from time to time, especially when used for long periods at the typewriter. There is still some pain of other joints here and there. Dr. Blount says that experience shows most of these residual pains will settle out in time.

But, the author can daily turn more bottle tops, and lift heavier loads, and wrestle playfully with another without screaming bloody murder!

And best of all, extreme apathy is gone, as is middle-of-day fatigue!

Can there be a better gift from one human to another, than this, that health and happiness is restored, and at no cost, except that of minor medicines?

Need the author state: I love Dr. Jack Blount and Professor Roger Wyburn-Mason, the first for courage, fortitude and charity, the second for wisdom, persistence and intelligence!

***

1. According to Professor Roger Wyburn-Mason, all forms of arthritis should be rested, as joint activity increases inflammation and pain and prevents healing.

Chapter IV

The "MIRACLE" Treatment

Recommended Treatments

To your family doctor, we say: Antiamoebics have never been considered for use against rheumatoid diseases because the various arthritis associations have not yet

investigated Professor Roger Wyburn-Mason's brilliant scientific work, published now since 1964.

You must decide if the prescriptions that follow are harmful to your patient. If not, is the cost involved worth a trial, considering the hopeless and insidious nature of the diseases?

Many cooperating physicians are using the protocol that follows:

The Roger Wyburn-Mason & Jack M. Blount Foundation
for Eradication of Rheumatoid Disease
7111 Sweetgum Drive SW, Suite A
Fairview, Tn 37062-9384; (615) 799-1002

The Rheumatoid Disease Foundation, now The Arthritis Trust of America
A non-profit, charitable, tax-exempt organization

The Rheumatoid Disease Foundation through its cooperating physicians in a committee chaired by Robert Johnson, M.D. (Charleston, SC) has established the following standards of practice when treating rheumatoid disease. These are suggested standards. Many physicians will exceed these basic standards. What follows is an outline developed through research and experience of cooperating physicians. A SIMPLE AND INEXPENSIVE CURE/REMISSION FOR RHEUMATOID DISEASES IS SET OUT IN WHAT FOLLOWS. DRAW YOUR DOCTOR'S ATTENTION TO THE MEDICATIONS THAT OTHER PHYSICIANS ARE ALREADY USING EFFECTIVELY. IF YOU DO NOT HAVE A FAMILY DOCTOR, WRITE FOR OUR LIST OF COOPERATING PHYSICIANS.

Your family physician should know that there are at least two genus of limax amoebae (one-celled animal life) that cause Rheumatoid Disease if you are genetically susceptible to it, or its products: Acanthamoeba and/or Naegleria.

Within these two genus, are many species, and strains within species, and they vary considerably in their ability to adapt to various antiprotozoal agents. Where one antiamoebic will kill one organism inside they body, another will not, and which organism affects you can only be learned by trial and error. Success rates from the first application of the treatment program listed below varies from 78% to 95% depending on which physician and which group of patients is being treated. The success rate is higher whenever further applications of the appropriate antiamoebic is used.

If the first treatment does not bring about a Herxheimer reaction, the physician is advised to move to another antiamoebic, and in any case, both this Foundation as well as any of the cooperating physicians will be more than happy to share their experiences.

The Foundation cannot, of course, be responsible for mal-application, mis-application, or inappropriate treatment of any kind, and again suggests that all treatment, if possible, be through your family physician.

Rheumatoid Disease Protocol

The central theme of treatment is based on the preliminary work of Professor Roger Wyburn-Mason and Jack M. Blount, M.D., and later findings or Robert Bingham, M.D.; it also seeks to introduce physicians to alternative or extended courses of treatment that have been found to be useful by other physicians in the organization, the goals being to: (1) arrest rheumatoid disease, (2) repair damage caused by rheumatoid disease, (3) further the maintenance for wellness.

This protocol is intended as an outline, and cannot serve as a "course in treatment" for rheumatoid disease. It is necessary for each physician to pursue his/her own intricacies of modalities mentioned.

I. Diagnosis: Shall be made on the basis of

A. Patient History - to include

1. Time of onset

2. Degree of disability

3. Family history

4. Remissions and exacerbations

5. Contributing factors

6. Previous treatment modalities and results thereof

7. Activity pattern

8. Medications being taken

B. Physical Examination

1. General appearance

2. Weight and height

3. Blood pressure and pulse

4. Head and neck

5. Cardio-vascular system

6. Abdomen

7. Musculo-skeletal system (to include evaluation of joints)

C. Laboratory testing

1. Urinalysis

2. SMAC -24

3. Rheumatoid pane (to include sedimentation rate and CPR)

4. Analysis of synovial fluid (when present)

5. Other (as indicated)

6. Electrocardiogram

7. X-rays of affected joints (if indicated)

8. Any of the above that have been performed by another physician within the past 60 days may be utilized at the discretion of the treating physician.

II. Treatment: (several treatment regimens are available)

A. Oral Medications

1. Nitroimidazoles

(a). Metronidiazole

(b). Tinidazole

(c). Clotrimazole

Whichever nitroimidazole is used, the dosage (modified by weight) is the same: 2 grams for two (2) days each week X6 weeks. (Children 250mg/25 pounds body weight).

2. Furazolidone (Furoxone) 100 mg q.i.d. X1 week

3. Iodoquinol 650 mg t.i.d. X3 weeks

4. POTABA 2 grams 6 times daily X2 weeks

5. Allopurinol 300 mg t.i.d. X1 week (this in conjunction with one of the above 5 antiamoebics - 1.(a), 1.(b), 1.(c),2,3. --used together acts as broad spectrum antiamoebic).

6. Rifampin or Rimactane 600 mg daily X1 month (If reactions are severe, stop treatment immediately).

B. Injections

1. Intraneural Injections (technique of Dr. Paul K. Pybus, Dr. I.H.J. Bourne)

2. Cleveland Clinic treatment (method of Jack M. Blount, M.D.: Lumbar subarachnoid injection of 2.5 cc of 0.3% procaine with 20mg Depo-Medrol)

C. Nutrition (to include vitamin and mineral supplements as well as counseling relative to diet. [Updated guidelines are now available through The Arthritis Trust of America for this nutritional support. Ed. S.C.]).

D. Steroids -- the use of Prednisone 20 mg daily X5 days or Depo-Medrol 40 mg injection X1 will reduce considerably the Jarisch-Herxheimer reaction often seen when initiating therapy (See General Information).

E. Ancillary treatment modalities (as used by various advisory committee members).

1. Mega vitamin dosage (Prosch, Reich, Bingham)

2. Chelation therapy (American Academy of Medical Preventics -- AAMPS)

3. Hot mineral baths (Bingham)

F. Return visits

1. Return visits should probably be in 1 week, 3 weeks, 6 weeks, then every 3 months thereafter.

2. Preventive maintenance: It usually helps to prevent the recurrence of rheumatoid disease if he patient is given a round of treatment with Allopurinol at 6 months post-original treatment and every 6 months thereafter. If symptoms are present, the entire original treatment regimen should be repeated. Allopurinol can cause a very severe reaction on the second round of treatment -- Wyburn-Mason).

G. General Information

1. Most patients will need counseling about diet and nutrition.

2. Explanation of the Jarisch-Herxheimer reaction often will prevent patient drop-out in many cases.

3. Since Metronidazole is the only nitroimidazole currently available in the United States, it is probably the drug of choice for beginning treatment.

4. Utilization of the "Cleveland Clinic" injection and intraneural injections should probably be reserved until the individual physician has had the opportunity to learn the technique from a physician already using it.

5. Most of the foregoing treatment is directed toward rheumatoid disease. Osteoarthritis has been found to respond much less dramatically, although it does often show some degree of improvement. (Best results seem to be achieved with intraneural injections.)

6. Rationale for treatment with antiamoebics: Based on Dr. Roger Wyburn-Mason's work which demonstrated free-living limax amoebae to be the causative agent in rheumatoid disease, amoebicidal drugs have been postulated as a treatment of choice. When these drugs kill the organism, the release of foreign proteins usually results in a Jarisch-Herxheimer reaction (similar to the old arsenic treatment for syphilis). This results in a temporary generalized increase of rheumatoid symptoms with the administration of an antirheumatic drug.

7. Drug reactions

(a). Rifampicin -- violent Herxheimer. In this event, discontinue treatment with rifampicin at once.

(b). Allopurinol -- leg pain, temperature spike, chills, sweating, rash on body and face.

This protocol is subject to revisions (additions, deletions, changes) as The Rheumatoid Disease Foundation, now The Arthritis Trust of America completes relevant research.

Perry A. Chapdelaine, Sr.

Executive Director/Secretary

Revised 1985: Physicians & Scientists Committee

Since alcohol in presence of antiamoebic (metronidazole, Allopurinol) (or antibiotics) makes some people sick, it may be best not to take any alcohol during period of treatment of six weeks. (The medicine will stay in the body during the first four weeks. Also sometimes alcohol destroys certain chemical compounds and, in the case of several antiamoebics, alcohol is definitely not a good idea.

If you are taking other medicines, such as anti-inflammatory drugs for arthritis, and other than cortisone compounds, you may continue taking them. There will be no conflicting side-effects. However, for the most part, it is best if you check with your family physician when determining possible contra-indications of other medicines.

Cost of these medicines may vary from $37 to several hundred dollars depending upon your treatment, the pharmacy with which you trade, and the length of the treatment.

Please keep in mind that every physician including your own will have additional treatment modalities in mind: nutritional guidance, exercise, strengthening of the immunological system by various techniques, chelation therapy, hot baths, and so on. You should understand what your treatment will consist of in advance, and why, before rejecting your physicians directions out of hand.

However, in no case should you permit the use of gold shots or penicillamine at the same time you are taking antiamoebics.

The response of patients to the above medicines is often inhibited by long-continued, previous treatment with gold injections, penicillamine or corticosteroids.3 East patient must be considered and studied independently, for the most effective treatment.

And while the former use of gold shots and/or penicillamine does not necessarily mean that you will not respond (many do), it may mean that you must find a way to chelate out the residual gold prior to having effective antiamoebic treatment.

F.M. Logsdon, M.D. (TX: deceased) developed a technique that seemed effective using the American Academy of Medical Preventics (AAMPS) treatment protocol for chelating out residual gold, following the progress through several chelations via laboratory tests.

On the Herxheimer

From experience, your primary rheumatoid arthritic symptoms should begin to be alleviated within a day or so, although it is not unusual for several weeks to go by before changes are observed.

In particular, one should know that the fever and swollen feeling and swollen appearance of joints may be increased at first. The symptoms may appear very similar to flu symptoms: flushing of skin, sweating, aching bones, fever, headache, sometimes running nose . . . like a foreign protein reaction. This is the Jarisch-Herxheimer reaction which is a "transiently increased discomfort in skin lesions and temperature elevations occurring . . . after start of antiamoebic treatment . . .," according to a medical dictionary.

You may also be quite allergic to the proteins (and /or the toxic products) of the rapidly dying protozoa that swarm in your body, and the Jarisch-Herxheimer reaction is related to that "allergy," a phenomenon very similar to a serum reaction.

However, despair not! Within days to weeks at most, this reaction (if you have it) will be lessened, and you will be pleasantly surprised!

***

The use of antiamoebics for treatment of Rheumatoid Disease was introduced by Roger Wyburn-Mason in 1964 in the Henry Kimpton/Charles C. Thomas publication, A New Protozoan and also at the IXth International Conference of Chemotherapy held in London, England in July 1975.

Chief antiamoebics recommended by The Rheumatoid Disease Foundation, now The Arthritis Fund, are imidazoles where substitution has been made in the ONE position (Dr. John R.A. Simoons, Pharmacology).

These compounds are amoebicidal in vitro against species of Naegleria and Acanthamoeba.

Metronidazole does not fit in the above classification, and is not amoebicidal in vitro against the named genus. Since Metronidazole works in vivo we speculate that one of its two chief metabolites, both azoles, and resulting from intestinal bacterial action, may be the active substance(s). [And some of these related compounds may also be effective against Candida albicans, Cell Wall deficient candida, Cell Wall Deficient bacteria, and macrophages believed to be responsible for autoimmune activity, which may have been what Wyburn-Mason had identified as amoebae. The appearance of all these single celled forms are nearly identical. See The Journal of the Academy of Rheumatoid Diseases, vol 1, no 3. Ed. S.C.] (Metronidazole is the only Nitroimidazole available in the United States). Antibiotics, of course, can knock out desirable microflora. [Acidophilus supplementation was later recommended partly to help the body metabolize Metronidazole into its effective metabolites, and partly to make up for the destruction of desirable microflora important in digestion. Ed. S.C.]

Wojtulewski evaluated clotrimazole in a double-blind study, finding that compound "effective in the treatment of Rheumatoid Arthritis and superior to Ketoprofen." ("Clotrimazole in Rheumatoid Arthritis," Annals of the Rheumatic Diseases, 39: 469-472; 1980.)

The Rheumatoid Disease Foundation, now The Arthritis Trust of America, is funding placebo controlled, double-blind studies at Bowman Gray School of Medicine, Wake Forest University, Winston-Salem. ND (Chief Investigator, Robert A. Turner, M.D., Chief, Rheumatology Section).

The Rheumatoid Disease Foundation, now The Arthritis Trust of America, following the life-time work of Professor Roger Wyburn-Mason, views Rheumatoid Disease as consisting of perhaps more than 100 different presenting symptoms, depending upon which tissues are affected by which genus, species, or strain of limax amoebae [abnormal macrophage, Cell Wall Deficient bacteria, candida strain, etc. Ed. S.C]. Key to understanding the treatment protocol is observing the Jarisch-Herxheimer effect (flu-like-symptoms) accompanying the use of antiamoebics. When treating Leprosy, the phenomenon is known as Lucio's Phenomenon. Treatment of tuberculosis, and the historical arsenic treatment of syphilis creates the same phenomenon.

While The Rheumatoid Disease Foundation, now The Arthritis Fund, views the limax amoeba theory as being the most probable (and workable) hypothesis in explaining and bringing about cure/remission of Rheumatoid Diseases, it recognizes that a multiplicity of factors are at work, including genetic susceptibility, nutrition and other good health rules; and it does not view free-radical explanations as being inconsistent with the limax amoeba hypothesis.

One difficulty seen in hindsight has been in distinguishing between the disease as an on-going process and the damage done by the disease.

The disease can be stopped but many of the symptoms having resulted from the disease -- the damage done -- may prevail, requiring other treatment protocols: nutrition, chelation, exercise, surgery, et. al.

Open studies, using various antiamoebics in the treatment of Rheumatoid Diseases by Drs. Robert Bingham, Gus J. Prosch, Jr., Paul K. Pybus depict results varying from 78% to 95%. [Anna Boland's, M.D. (Korea) figures are less successful while Sheldon Nelson's, D.O. (Michigan) are more successful.]

Traditional, anticipated placebo effects in an open study would not be greater than about 33%. Results showing 78-95% are considerably beyond placebo expectation.

[Wyburn-Mason/Pybus intraneural injection studies show excellent results when treating pains of Rheumatoid Disease and Osteoarthritis. Additional independently conceived and developed intraneural injection studies are available from Dr. I.H.J. Bourne (Richmond, Thorndon Approach, Herongate, Brentwood CM 13 3PA, England).]

In a letter to Dr. John R.A. Simoons, July 7, 1984, Gus J. Prosch, Jr., M.D. says;

Let me make some general statements concerning past observations and studies that I have concluded to be the truth in treating Rheumatoid Disease with antiamoebic drugs.

1. I recently completed a research project concerning the treating of 200 patients with Rheumatoid Disease with antiamoebic medication. The primary antiamoebic used was Metronidazole, and when the desired response was not forthcoming, I used other

antiamoebics such as Allopurinol, Furazolidone or Rimactane. Final analysis demonstrated 78% good to excellent (cured or in remission) results and 22% showing poor to no result. All patients having a favorable response had some Herxheimer

reaction and those showing poor to no response demonstrated very mild to no Herxheimer reaction. Incidentally, no serious side effects were observed from the medication.

2. The amoeba (or offending agent) can involve (or infect) any body tissue, organ or system.

3. If involved (or infected), that tissue, organ or system can demonstrate some form of a Herxheimer reaction when antiamoebic medication is introduced into the body.

4. With the initial introduction (1st week) of the antiamoebic medication, the Herxheimer reaction can be so severe that patients become fearful that the medication is doing them great harm and may want to stop the treatment. For this reason, a single initial injection of 20-40 mg of Depot Medrol is usually given to lessen the severity of the reaction.

5. After the second week of medication, the reaction gradually begins to subside, as fewer amoebae (or offending germ or agent) are killed and less antigen is released in the body.

6. If a patient has any Herxheimer reaction following the sixth week of medication, the patient is still infected and further treatment is indicated.

7. Long standing or chronic Rheumatoid Disease responds slower than acute disease.

8. If a patient being treated with antiamoebics does not have a Herxheimer reaction, the patient simply does not have Rheumatoid Disease or the particular amoebae (or offending agents) are resistant to the particular antiamoebic medication being given. [There is also a possibility of lack of appropriate stomach bacteria/flora to metabolize the imidazoles and/or enzyme deficiencies in the patient. Ed.]

9. Herxheimer reaction signs and symptoms:

a. General and usual: Sweating and especially night sweats, diarrhea, nausea, vomiting, headache, fever, general malaise, flushing of skin, anorexia, aching bones and "flu" symptoms resembling a serum reaction.

b. The inflamed and affected tissues become more inflamed and tissues previously unknown to be involved become inflamed.

c. If the urinary bladder tissues are infected, patients may develop signs of full blown cystitis.

d. If the heart, pericardium or cardiac tissue is infected, the patient may develop some paroxysmal auricular tachycardia, premature ventricular contractions or ectopic beats.

e. If the brain or meninges are infected the patient may develop severe (temporary) depression, lethargy, generalized weakness, temporary memory loss (personal experience), irritability along with headaches.

f. If the mouth tissues are infected, a bitter and/or metallic taste may be noted along with mild shedding or peeling of the mucosal tissues. This has also been noted in the rectal tissues.

g. When the periosteal tissues and skeletal muscle tissues are involved, fairly severe bone pain usually accompanied by severe muscle pains and spasms may be observed, usually at night.

h. When the lungs and bronchial tissues are infected, the patients may develop bronchitis symptoms and occasionally pneumonitis (resembling viral) has been observed.

From the above, one can easily see that most all of the previously observed side effects of [antiamoebics] may also be simply manifestations of the Herxheimer reaction. Therefore, a clinician that is not totally knowledgeable concerning these possible signs and symptoms could easily mistake the Herxheimer reaction for possible side effects of the [antiamoebic]. Should this information not be taken into consideration, a misleading and false evaluation of any adverse experiences by various patients caused by the [antiamoebics] will be inevitable . . . the medicine could be labeled more dangerous than it actually may be, and the aggravated symptoms could be misconstrued as an intensification of the disease being treated. The information and the above facts must be considered in evaluating [antiamoebic] effectiveness and side effects [when treating [patients].

***

1. Herxheimer, K., Dtsch. Mewd. Wschr., 1902, Vol. 28, p. 895.

2. From Phil Gunby, JAMA, "Allopurinol Treatment for Protozoan Infections?" Vol. 240, No. 18, Oct. 27, 1978, p. 1941-1942; The Limax amoeba has a fatal flaw -- a unique enzyme system that transforms Allopurinol into a toxic (to the amoeba) adenine analog, 4-amino pyrazolopyrimidine. This analogue then is incorporated into their nucleic acid, with fatal results for the protozoan.

3. The Causation of Rheumatoid disease and Many Human Cancers - A New Concept in Medicine - A pr‚cis and Addenda Including the Nature of Multiple Sclerosis, The Arthritis Trust of America, 7111 Sweetgum Drive SW, Suite A, Fairview, TN 37062-9384, 1983, p. 3.

Prior to F.M. Logsdon's (M.D.) recent death, he suggested that residual gold could be chelated from the patient by means of several EDTA treatments, using American Academy of Medical Preventics protocols. Following up the residual gold measurements by means of sera tests, he was apparently successful with several patients who thereafter responded to antiamoebics. Whether or not this will work for all, most, or many is unknown.

Chapter V

Cooperating Physicians and Scientists

How to Contact Them

The Rheumatoid Disease Foundation, now The Arthritis Fund, recommends that you take this book and its described treatment to your family physician. He/she will be given every cooperation, without charge, to help you get well.

If your family physician is unwilling to learn this treatment, then we suggest that you search your city for a physician who is open-minded. After all, it is your file - not the physician's - and you have a right to the treatment of your choice.

Try, first, those physicians who are involved with preventive medicine as they are often more open-minded than the strict allopathic physician, who wants to prescribe standard drugs according to standard practices, whether you get well or not.

And do not be afraid to try osteopathic physicians, [chiropractic physicians, and naturopaths], the D.O., D.C., and N.D., after their names being just as significant as an M.D.

If all else fails, then you may write to The Arthritis Trust of America, 7111 Sweetgum Drive SW, Suite A, Fairview, TN 37062-9384, [(615) 799-1002] for a current list of physicians who've agreed to use these procedures.

There are many physicians scattered across the United States who use similar or equivalent procedures. How many are to be found in other countries is unknown, but The Rheumatoid Disease Foundation, now The Arthritis Fund, will refer where it can.

A list of physicians who've agreed to use The Rheumatoid Disease Foundation's treatment protocols - as of the printing date of this edition - may be found in the rear of this book.

Table of Medicines

Robert Bingham, M.D., Jack M. Blount, M.D., Archimedes A. Concon, M.D., John R.A. Simoons, Ph. D., and Professor Roger Wyburn-Mason have kindly included the following table of medicines for physicians and other readers. All but one B vitamin are anti-free-living amoebic drugs, the prednisone being given temporarily to counter the Jarisch-Herxheimer reaction if the physician and patient desire: [the therapeutic uses of the supplements or herbs, boron, copper, protein digestive enzymes, Yucca extract, and bile salts as alternatives or adjuncts to the following medications are also available through The Arthritis Fund library of articles, books and journals]

[Note: The following table was prepared in 1982]

Chemical

Generic Name Compound Group Brand Name Manufacturer

allopurinol pyrimidine Zyloprimr Burroughs-Wellcome

Clotrimazole* imidazole Mycelexr Dome

clotrimazole imidazole Lotriminr Delbay

diiodohydro-oxyquinon oxyquinoline Yodoxinr Vitarine

furazolidone nitrofuran Furoxoner Eaton

metronidazole nitroimidazole Flagylr Searle

nimorazole nitroimidazole Emtrylr Salsbury

nimorazole nitroimidazole Naxoginr Erba

ornidazole nitroimidazole Tiberalr Roche

prednisone*** glucocorticoids Deltasoner Upjohn

rifampin rifamycin B Rifadinr Dow

rifampicin rifamycin B Rimactaner Ciba

tinidazole nitroimidazole Fasigynr Pfizer

potassium para amino

benzoate vitamin B POTABAr Glenwood

*Available in USA only as vaginal tablets and cream.

** Not yet released by FDA for use in USA. (Tinidazole, for example, is available in Australia as Fasigynr 500; but known as Tinidexr in Mexico without prescription; Most nitroimidazoles can be obtained through a compounding pharmacy in the United States)

***Prednisone is not an antiamoebic.

Tony Chapdelaine, working under Dr. Jack Neff (protozoologist) at Vanderbilt University, conducted extensive in vitro chemosensitivity tests on Acanthamoeba culbertsoni, Acanthamoeba castellanni, and Naegleri gruberi, finding a great variation in response to the drugs listed above, and others not listed. This variation begins to explain why some will respond immediately to treatment, while others must go through a course of several antiamoebics before acquiring a Herxheimer, and subsequent health. One medicine will kill one limax amoeba, but not another, will encyst one, but ignore another . . . Considering that there are more than 300 different species and strains within the above two classifications, each with a different sensitivity to various chemicals, one begins to understand the variable human responses to antiamoebics.

If the amoeba is killed in vitro, it is likely to be killed in vivo. But if it is not killed in vitro, it may or may not be killed in vivo.

A classic example, is metronidazole, which does not affect any of the above species in vitro. It must be, therefore, that one or both of the two metabolites (both azoles) of Metronidazole -- (1-acetic-2methyl-d-nitroimidazole) and (1-[2-hydroxyethyl]-2-hydroxymethyl-5-nitroimidazole) -- kill the organisms in vivo. Possibly the small number who do not respond to metronidazole (when given protocol quantities) do not have the appropriate microflora that are necessary for producing the two active metabolites. If this is true, then physicians should consider supplementing their patient's treatment with the restoration of the necessary intestinal bacteria [with L. acidophilus].

Diiodohydroxyquinon (Iodoquinol or Yodoxin), a recent addition by Robert Bingham, M.D., was found to kill Naegleria, but not Acanthamoeba. Clotrimazole, on the other hand, was effective in killing both genus in vitro, and is known to be effective in vivo, thus the reason for starting Rheumatoid Disease Foundation double-blind studies with clotrimazole.

Consider also that the Limax amoeba, like bacterial pathogens, is capable of losing sensitivity to one antiamoebic, and therefore each physician must consider the prospect of switching from one antiamoebic to another, especially for those who prove to be especially sensitive to the amoeba (or its products), and especially when considering the six-month anti-reinfection treatment.

Some physician do not believe that prednisone should be used to mask the Jarisch-Herxheimer reaction, that it is better to discontinue treatment until the "allergy" reaction dies down, and then to begin antiamoebic treatment again.

Keep in mind that while physicians' experiences and opinions may vary, results are what's important!

A Simple Plea To Sincere Physicians

On Behalf of all Board Members of The Rheumatoid Disease Foundation now The Arthritis Trust of America by

Gus J. Prosch, Jr., M.D.

"If you are sincere and truly desire to relieve the agony and suffering of your arthritic patients, I beg of you to give the previously recommended treatments a trial on your rheumatoid and osteoarthritis patients. I promise you that you will receive far superior results in relieving your patients' pain, suffering and disability than anything you have ever used before. You will be treating the cause of the rheumatoid disease and not simply the symptoms. You can now offer these severely neglected patients far more than a simple 'hope' of finding relief which conventional methods of treatment cannot even offer. You will be offering them total relief which will literally change the entire lives of these patients and their families. You will never find the satisfaction and pleasure of helping your fellowman any greater than by using these techniques to treat arthritic sufferers. You will completely and thoroughly understand what I mean when certain patients come to you in a wheelchair and, after receiving your treatment and injections by the above recommended techniques, they refuse to use the wheelchair to leave your office.

What joy What contentment! What satisfaction!

Good luck and God be with you!!!"

Chapter VI

Professor Wyburn-Mason's Theory of Protozoal Cause of Many Hitherto Unrelated Diseases

The Prevailing Medical Theory

Are you surprised that a simple thing, like an amoeba, is the basis, the primary cause of all your "incurable" rheumatic disease problems?

The author was, so much so that he visited Vanderbilt University Medical Library to consult with two current books of internal medicine. The following is quoted:

Internal medicine book 11: "On the basis of current evidence, it is more likely that rheumatoid factors are products of the host response to a primary event. The nature of this postulated primary event is still unknown, but there is renewed interest in an old concept that microbial disease may underlie the development of rheumatoid arthritis."

Internal medicine book 22: "The etiologic factor(s) [causes] that set into motion the above immunological events is not known. An infectious agent, viral or bacterial, may will initiate the immunologic and subsequent inflammatory process in rheumatoid arthritis, but this hypothesis needs experimental proof."

Wyburn-Mason's Findings

Professor Roger Wyburn-Mason's 479 page book The Causation of Rheumatoid Disease and Many Human Cancers - A New Concept In Medicine (1978) and his Addenda (1983), upon which this book is based, are textbooks written for medical doctors and researchers in micro-biology, and cannot be read easily without a medical dictionary.

Wyburn-Mason's proofs, arguments, and case-histories are exceedingly well done and lead the reader to but one conclusion: Protozoa that have been with man since his earliest evolution are still with him, and, like the bacterial theory of the origin of various diseases, these same amoebae can be cited as being the primary cause of many otherwise and hitherto unexplained diseases.

Indeed, since arthritic deformities are found in fossilized bones of animals that preceded man's evolution, his Homo Sapiens structure, it must follow that this protozoan or one of a similar genus followed man's every evolutionary step.

State of Art in Medicine

By way of placing what follows in context, the author would take the liberty of itemizing some fundamental principles that the reader should consider:

1. Clinical applications in medicine always lag behind research, sometimes by as much as a generation or more. The U.S. Food and Drug Administration tightly - sometimes too conservatively - controls the use of various drugs for experimental purposes, thus inhibiting your family physician from taking advantage of early work done by others, often overseas. State medical boards, rightly or wrongly, inhibit medical practices not approved by peer review.

2. The increase in malpractice suits against physicians has brought about an almost sterile inclination to practice any kind of medicine except that which is "acceptable" by text-book peer review. If the text-book says that something cannot be cured, and that one should, however, treat symptoms, then that is what your doctor will tell his patient, and what he will do, respectively. It keeps him out of trouble, although it has virtually no chance of curing you.

3. The theory of protozoa as sources of disease in the human body has only recently been opened by the general medical profession, and the theory has only now been fully developed by the research of Professor Wyburn-Mason and shown in the above named book.

4. There is already a well-developed theory of bacteria as primary source of disease, a well-developed theory of fungus and yeasts as cause of disease, a growing development of viral cause of disease, a new theory of viroids and prions (stripped-down virus), and a very sporadically developed theory of protozoan (amoeboid) cause of disease, until now.

5. Consider the original, historical impact of the theory of bacteria as primary source of disease. Once you get the idea that there are many different species and strains of bacteria and that, when they invade humans, they each affect different systems and organs in different ways, one can begin to understand the parallel protozoal theory. Broad-spectrum antibiotics can be used interchangeably against microbial caused diseases thereby demonstrating many different symptoms and bringing about a cure of each. So it is with the protozoan theory of disease. There are over 300 species of amoebae identified to date, some of which are pathogenic, and certain broad-spectrum anti-protozoal medicines will knock them out, no matter what the ultimate symptoms may appear to be and no matter how those symptoms are currently classified in medical literature. Remember, symptoms classifications are only that, not descriptions of primary causes!

6. According to Professor Roger Wyburn-Mason's work, there are certain protozoa that are called Limax (Limax amoeba: meaning slug-like amoeba) that are found in virtually all human and animal tissue from birth onward. Similar to the ever-present bacteria, these Limax amoebae may be pathogenic and may affect different parts of the human body in different ways, depending upon their species, your genetic heritage, and upon which systems or organs they invade. Their hostile invasions are apparently triggered off within the body in the same manner and for the same reasons that multiplication of hostile bacteria begins.

7. These Limax amoebae were not found in many diseases previously because (a) it was thought to take special staining techniques to find them, (b) when they are found they are often mistaken for the body's own macrophages or poorly stained leukocytes, (c) even when animals are inoculated with them and similar diseases produced in the animals, the amoebae are difficult to find in the lesions, although the live protozoa can be separated from tissue by special techniques.

8. In Chapter IV of Professor Wyburn-Mason's book (pages 120-1) it is stated that the Limax amoebae were isolated from:

a. all the tissues of all cases of collagen and auto-immune diseases examined, including cases of rheumatoid arthritis, systemic lupus erythematosus (dise