The Mystery
of Obesity
by Majid Ali, MD
This article was provided by:
Aging Healthfully Magazine
Note: The information on this website is presented for educational purposes only.
It is not a substitute for the advice of a qualified professional.
If there is any mystery about the cause of obesity, it is
locked up in the workings of two cells: the myocyte and the adipocyte.
The myocyte (muscle cell) is the cell where the action begins and
adipocyte (fat cell) is where it ends. The study of these two types of cells reveals the
true nature of obesity. It is through an understanding of the structure and function of
the two cells that we can begin to discern the marvels of biology that keep us lean and
energetic. It is also through an understanding of these two cells that we clearly see the
utter irrationality of the prevailing ideas of dieting for weight loss. Life span foods
nourish these cells; aging-oxidant foods paralyze their life-sustaining enzyme systems.
Fat-burning exercises energize their fat-burning enzymes; sugar-burning exercises energize
their sugar-burning enzymes. Antibiotics, pesticides and fungicides destroy their enzymes
as do toxic metals and industrial pollutants.
Obesity is a problem of emaciated myocytes and bloated adipocytes.
Obesity is not a problem of the mind. Dieting is not a solution to the problem of obesity.
Those who choose to diet do not know the biology of these cells (or do not choose to learn
about these cells for reasons only they understand).
THE ADIPOCYTE
An adipocyte is a tiny cell packed with triglyceride fat. There are
approximately 30 billion adipocytes in the human body. Nature designed the adipocyte as a
tiny packet of stored energy. Energy is stored in an adipocyte as a tiny droplet of
triglyceride fat, about 0.5 microgram in weight (A teaspoon can hold roughly 6 million
micrograms of sugar). An average adult carries about 15 kg (33 pounds) of fat in his 30
billion adipocytes. Since one gram of fat contains 9 calories, it follows that an average
adult has 135,000 calories stored in his adipocytes. This depot of energy can sustain an
adult through a 40-50 day fast.
The term triglyceride refers to a molecule formed by three fatty acids
linked together by a single molecule of a specific type of alcohol called glycerol. The
types of fatty acids included in triglycerides in adipocytes reflect the composition of
fatty acids in the diet. Life span foods fill the adipocytes with unspoiled, unoxidized
fatty acids; aging-oxidant foods lead to the storage of oxidized fatty acids. Studies have
shown that diets rich in life span oils such as oleic acid (olive oil is an important
source of this oil) lead to a higher quantity of healthful fatty acids in adipocytes.
THE CELLULAR INTELLIGENCE OF THE FAT CELL
The fat cell is an intelligent cell. The wisdom of this cell shows
itself in how it orchestrates the workings of the molecules that reside on its surface and
those that live within it. There are molecules on its surface that it uses as hooks. It
literally fishes for molecules it needs from the soup of life fluids that bathes its
surface. These molecules include various hormones and other important
"intelligence" molecules of the body. It has its own enzymes, and it has
messenger RNA molecules that it uses to make daughter enzyme molecules.
The cell membrane of the fat cell is a marvel of biology.
* It separates internal order from external disorder.
* It serves as the principal clearing house for the cellular
intelligence data.
* It transforms intelligence data into physical energy and molecular
changes.
* It keeps under surveillance the intrinsic cellular self-destruct
mechanisms.
* It alters its own image and structure to respond to changes in its
environments.
* It serves the cell as its skin, its bowel, its kidneys, its lungs, all
rolled in one.
* It influences the regulatory mechanisms for cellular growth,
differentiation and reproductive potential.
* In essence, it thinks for the cell.
The adipocyte watches out for dangers. It fends for itself. It has
sentinel molecules. It has gatekeeper molecules. It has builder molecules and scavenger
molecules. It has molecules which it is willing to sacrifice and others which it guards
with its life. It has slave molecules and master molecules. It has spies and messengers.
The adipocyte has clear ideas of its internal organization, and it is capable of
responding and adapting to preserve that order.
CELLULITE: THE GRAVEYARD OF DEAD FAT CELLS
There is an absolute limit to how much any cell can suffer. And so it
is with fat cells. When toxic cyclic and trans fatty acids and fat peroxides coat a fat
cell, the cell suffocates and slowly dies. Why does it happen? It happens because the cell
cannot breathe through the plastic layer of these denatured fats on its surface membrane.
The molecules it needs cannot come in. The molecules it wants to rid itself of cannot go
out. The molecular menagerie of the cell, the ever-changing kaleidoscope of life, comes to
a standstill. The fat cell dies. Then another cell dies, and then another. The dead bodies
of these cells coalesce to form the chunks of dead fat we call cellulite. Think of dying
and dead fat cells next time you see a child being fed french fries soaked with toxic oils
and a greasy hamburger cooked with toxic fats. And then think of what dieting can do to
the graveyards of dead fat cells. Dead fat cells in the body cannot be brought back to
life by starving the whole body with dieting. Next, look at the label of the frozen foods
that dieting experts package for you. Denatured, oxidized oils are not hard to spot. One
clue: Almost all cholesterol-free items in these foods are made with processed oils
contaminated with toxic fats. So stay away from cholesterol- free fats.
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