CELL DEATH

COENZYME Q10

1. Rabbit eyes were treated with CoQ10 (20% solution) and vitamin E (0.04% solution) for 3 days before keratectomy surgery. The eyes treated with the supplement had fewer apoptotic (cell death) events than the untreated eyes.

J Refract Surg. 2002 Mar-Apr;18(2):135-9. 
Concomitant effect of topical Ubiquinone Q10 and vitamin E to prevent keratocyte apoptosis after excimer laser photoablation in rabbits.
Brancato R, Fiore T, Papucci L, Schiavone N, Formigli L, Orlandini SZ, Gobbi PG, Carones F, Donnini M, Lapucci A, Capaccioli S.
PMID: 11934201

ELLAGIC ACID
(1 micromole = one-thousandth of a gram-molecule)

2. Ellagic acid (5 micromole per liter) and quercetin (10 micromole per liter) increased cell death and decreased proliferation of cancer cells.

J Nutr. 2003 Aug;133(8):2669-74. 
Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells.
Mertens-Talcott SU, Talcott ST, Percival SS.