CANKER SORES

ZINC

1. Compared to placebo, daily doses of zinc (220 mg/day) for 1 month reduced canker sores, which did not recur after 3 months of monitoring.

Dent Mater J. 2003 Mar;22(1):21-9. 
Effects of zinc treatment in patients with recurrent aphthous stomatitis.
Orbak R, Cicek Y, Tezel A, Dogru Y.
PMID: 12790293

2. Daily doses of zinc (up to 660 mg/day) reduced the frequency of incidence of canker sores in patients with recurring oral ulcers and low zinc levels.

South Med J. 1977 May;70(5):559-61. 
Zinc sulfate supplementation for treatment of recurring oral ulcers.
Merchant HW, Gangarosa LP, Glassman AB, Sobel RE.
PMID: 870981